Sixty percent of QCG-treated animals (controls) survived through the 150-minute observation period. Hemodynamic and physiologic parameters, along with markers of coagulation, were recorded and analyzed. Animal survival, hemostasis, and blood loss were measured as primary end points. After 3 minutes of applied, direct pressure, fluid resuscitation was administered to elevate and maintain a mean arterial pressure of 60 mm Hg or greater during the 150-minute observation time. Free bleeding was allowed to proceed for 45 seconds before packing of QCG, QuikClot Combat Gauze XL (QCX), Celox Trauma Gauze (CTG), Celox Gauze (CEL), or HemCon ChitoGauze (HCG), into the wound. The femoral artery of anesthetized Yorkshire pigs was isolated and punctured. This study aimed to determine the efficacy of currently available hemostatic dressings as compared with the current Committee for Tactical Combat Casualty Care Guidelines standard of treatment for hemorrhage control (QuikClot Combat Gauze ). The development, testing, and application of novel hemostatic dressings may lead to a reduction of prehospital mortality through enhanced point-of-injury hemostatic control. Uncontrolled hemorrhage is the leading cause of preventable death on the battlefield.

Cities xl 2012 guide